Summary

Dataset 1

Experiments excluded

Mask

Get figure file: figures/preliminary_dset-1_figure-mask.png

Peak coordinates

Get figure file: figures/preliminary_dset-1_figure-static.png
Get figure file: figures/preliminary_dset-1_figure-legend.png

Explorer

Meta-Analysis

Estimator

Parameters use to fit the meta-analytic estimator.

Corrector

Parameters use to fit the corrector.

Corrected meta-analytic map: z_corr-FDR_method-indep

Explorer

The following figure provides an interactive window to explore the meta-analytic map in detail.

Slice viewer

This panel shows the the corrrected meta-analytic map.

Get figure file: figures/corrector_figure-static.png

Diagnostics

Target image: z_corr-FDR_method-indep

Significant clusters

    X Y Z Peak Stat Cluster Size (mm3)
Tail Cluster ID          
Positive 1 -52.00 -52.00 18.00 5.58 10200
1a -48.00 -56.00 24.00 4.99
1b -54.00 -56.00 12.00 4.53
1c -48.00 -58.00 32.00 4.27
2 2.00 58.00 20.00 4.78 14792
2a -2.00 54.00 -6.00 4.27
2b 2.00 56.00 24.00 4.27
2c 0.00 50.00 18.00 4.27
3 -2.00 -60.00 30.00 4.53 4816
3a -2.00 -62.00 40.00 3.74
3b -4.00 -52.00 28.00 3.48
3c 2.00 -58.00 38.00 3.48
4 56.00 -46.00 18.00 4.27 6592
4a 54.00 -42.00 8.00 3.74
4b 58.00 -38.00 16.00 3.19
4c 50.00 -46.00 0.00 3.19
5 46.00 -64.00 -4.00 4.27 3112
5a 46.00 -72.00 2.00 3.19
5b 46.00 -66.00 -10.00 3.19
5c 42.00 -74.00 -4.00 2.90
6 40.00 18.00 -2.00 4.27 6672
6a 32.00 20.00 0.00 3.48
6b 52.00 20.00 6.00 3.19
6c 32.00 16.00 0.00 3.19
7 -42.00 22.00 -2.00 4.27 5512
7a -34.00 24.00 -6.00 4.00
7b -38.00 18.00 -10.00 3.48
7c -42.00 30.00 12.00 3.19
8 32.00 -48.00 -16.00 4.27 5336
8a 24.00 -48.00 -12.00 4.00
8b 22.00 -48.00 -20.00 3.74
8c 28.00 -46.00 -10.00 3.74
9 0.00 14.00 50.00 4.00 5592
9a 0.00 6.00 48.00 3.74
9b 0.00 14.00 46.00 3.48
9c -4.00 6.00 54.00 3.48
10 -40.00 -46.00 52.00 3.74 3088
10a -40.00 -40.00 58.00 3.74
10b -40.00 -32.00 52.00 2.90
10c -38.00 -40.00 62.00 2.59
11 58.00 0.00 -18.00 3.74 2584
11a 46.00 4.00 -22.00 2.26
11b 48.00 -6.00 -18.00 2.26
11c 50.00 4.00 -20.00 2.26
12 12.00 12.00 -4.00 3.74 3728
12a 4.00 10.00 0.00 3.48
12b 8.00 10.00 -10.00 2.90
12c -6.00 10.00 0.00 2.90
13 -58.00 -22.00 6.00 3.48 2800
13a -56.00 -18.00 -2.00 3.19
13b -52.00 -14.00 6.00 2.90
13c -54.00 -22.00 8.00 2.90
14 -28.00 -6.00 58.00 3.48 1488
14a -34.00 -14.00 60.00 2.26
14b -28.00 -4.00 48.00 2.26
14c -26.00 -14.00 62.00 2.26
15 -30.00 -56.00 -20.00 3.48 2624
15a -26.00 -50.00 -14.00 2.59
15b -28.00 -48.00 -22.00 2.59
15c -22.00 -56.00 -20.00 2.59
16 44.00 16.00 26.00 3.19 1216
16a 50.00 20.00 22.00 2.59
16b 42.00 8.00 34.00 2.26
16c 46.00 10.00 22.00 2.26
17 58.00 -20.00 2.00 3.19 1376
17a 54.00 -14.00 -2.00 2.59
17b 58.00 -20.00 8.00 2.59
17c 56.00 -16.00 -2.00 2.59
18 -46.00 -66.00 -2.00 2.90 480
18a -54.00 -68.00 0.00 1.92
19 -48.00 -68.00 8.00 2.59 120
20 22.00 -56.00 56.00 2.59 656
20a 20.00 -64.00 58.00 2.26
20b 26.00 -60.00 54.00 2.26
21 -58.00 -44.00 34.00 2.59 856
21a -54.00 -50.00 40.00 2.59
21b -54.00 -42.00 34.00 2.59
22 48.00 -44.00 44.00 2.59 456
23 -16.00 -62.00 60.00 2.59 136
23a -24.00 -58.00 56.00 2.26
24 8.00 -78.00 48.00 2.26 200
25 26.00 -2.00 -20.00 2.26 248
26 26.00 -2.00 58.00 2.26 112
27 -58.00 -8.00 -12.00 2.26 456
27a -50.00 -2.00 -10.00 1.92

Label map: positive tail

Get figure file: figures/diagnostics_tail-positive_figure.png

FocusCounter

The FocusCounter analysis characterizes the relative contribution of each experiment in a meta-analysis to the resulting clusters by counting the number of peaks from each experiment that fall within each significant cluster.

The heatmap presents the relative contributions of each experiment to each cluster in the thresholded map. There is one row for each experiment, and one column for each cluster, with column names being PostiveTail/NegativeTail indicating the sign (+/-) of the cluster's statistical values. The rows and columns were re-ordered to form clusters in the heatmap.

Heatmap: positive tail

Methods

We kindly ask to report results preprocessed with this tool using the following boilerplate.

A multilevel kernel density (MKDA) meta-analysis \citep{wager2007meta} was performed was performed
with NiMARE 0.6.1 (RRID:SCR_017398; \citealt{Salo2023}), using a(n) MKDA kernel. An MKDA kernel
\citep{wager2007meta} was used to generate study-wise modeled activation maps from coordinates. In
this kernel method, each coordinate is convolved with a sphere with a radius of 10.0 and a value of
1. For voxels with overlapping spheres, the maximum value was retained. Summary statistics (OF
values) were converted to p-values using an approximate null distribution. The input dataset
included 1812 foci from 256 experiments. False discovery rate correction was performed with the
Benjamini-Hochberg procedure \citep{benjamini1995controlling}.

Bibliography

@article{Salo2023,
  doi = {10.52294/001c.87681},
  url = {https://doi.org/10.52294/001c.87681},
  year = {2023},
  volume = {3},
  pages = {1 - 32},
  author = {Taylor Salo and Tal Yarkoni and Thomas E. Nichols and Jean-Baptiste Poline and Murat Bilgel and Katherine L. Bottenhorn and Dorota Jarecka and James D. Kent and Adam Kimbler and Dylan M. Nielson and Kendra M. Oudyk and Julio A. Peraza and Alexandre Pérez and Puck C. Reeders and Julio A. Yanes and Angela R. Laird},
  title = {NiMARE: Neuroimaging Meta-Analysis Research Environment},
  journal = {Aperture Neuro}
}
@article{benjamini1995controlling,
  title={Controlling the false discovery rate: a practical and powerful approach to multiple testing},
  author={Benjamini, Yoav and Hochberg, Yosef},
  journal={Journal of the Royal statistical society: series B (Methodological)},
  volume={57},
  number={1},
  pages={289--300},
  year={1995},
  publisher={Wiley Online Library},
  url={https://doi.org/10.1111/j.2517-6161.1995.tb02031.x},
  doi={10.1111/j.2517-6161.1995.tb02031.x}
}
@article{wager2007meta,
  title={Meta-analysis of functional neuroimaging data: current and future directions},
  author={Wager, Tor D and Lindquist, Martin and Kaplan, Lauren},
  journal={Social cognitive and affective neuroscience},
  volume={2},
  number={2},
  pages={150--158},
  year={2007},
  publisher={Oxford University Press},
  url={https://doi.org/10.1093/scan/nsm015},
  doi={10.1093/scan/nsm015}
}